The Validation Processor
Say goodbye to copying and pasting into Excel spreadsheets by automating validation/verification
Why use the Validation Processor?
Most labs copy and paste validation/verification data into outdated Excel workbooks, before data analysis and manual translation of the results into a template validation report for accreditation purposes.
Though feasible for assays targeting single analytes, the time and effort required for multiple/multiplexed assays becomes untenable.
At ValidateLabs, we have created a solution that automates this entire process in minutes (versus days/weeks).
Feature overview
Calibration Review
Allows the exploration of different models for each analyte and batch, which can be overlayed or filtered where necessary. Residual plots and exclusion lists are also readily available here.
Model Selection
Allows users to define models to each target analyte. By default, linear models are selected. The user can also toggle the model selector function which assesses all calibration models (linear, quadratic, various weightings) and selects the best model for each analyte based on the datasets available.
Detection Limits
Defines the model equations and determines the limits of detection.
Carryover
Defines the percentage of carryover detected in blank samples subsequently analysed after a high calibration sample.
QC Analysis
Allows the exploration of assay accuracy and precision. Boxplots are generated to visualise change between batches and replicates. Accuracy and precision are calculated based on the default settings in the table below. These limits can easily be defined in the adjacent panel. Samples can be excluded using the exclusion table.
Dilution Integrity
Defines the assays ability to dilute samples with target concentrations that exceed the highest calibrator.
Stability
Explores the effect of storage conditions on the analyte concentration over time. These are plotted graphically to visualise any change.
Matrix Effects
Defines the effect of the sample matrix on the target analyte as a percentage.
Interference
Allows the user to explore interference from the internal standard, the matrix, and common analytes.
Validation Report
Summarises all experiments into a singular table for quick review. An export function is available here – this automatically generates a validation report based on the data and user-defined settings from each tab (where performed). The exports can be easily downloaded and reviewed as a Word document.
Settings
Standards-based
Developed in accordance with ANSI/ASB Standard 036, we have built the Validation Processor to align with ISO 15189 and ISO 17025 standards.